Dermal fillers are one of the most common treatments performed in medical aesthetics clinics but with so many products on the market, choosing which one to use can be challenging.

It goes without saying that safety should be the top priority but there are many other factors to be considered including efficacy, tissue integration, natural looking results, longevity, ease of use, ease of ordering, brand support and cost.

KYSENSE® is the latest innovation in dermal filler technology with many of the UK’s top clinics now making it their ‘go-to’ product for facial rejuvenation and contouring. So, what is KYSENSE® and why should you use it in your clinic?

1. Innovative advanced technology

KYSENSE® is an innovative hyaluronic acid (HA) dermal filler made by Kylane, a Swiss company with extensive experience and a profound understanding of HA, with a state-of-the-art manufacturing facility in Casablanca, Morocco. It has been developed by the scientific team behind the global market leading fillers.

KYSENSE® is manufactured using HA Protect technology which involves the extraction of destructive oxygen species during the manufacturing process, including during the crosslinking step. This significantly preserves the intrinsic properties of the long molecular weight hyaluronic acid chains and thereby improving suppleness, injection precision and projection capacity.

2. Clinical safety

KYSENSE® is CE marked under the Medical Devices Regulation by notifying body 2797 BSI Group (Netherlands). In the rigorous pre-clinical studies and the CE study involving 50 patients, 5 injectors and 1 independent assessor revealed no hypersensitivity, skin irritation, cytotoxicity, genotoxicity, tissue reaction, delayed sensitisation or any other serious adverse events at 12 months after the first injection (March 2018). The study has been monitored by the French CRO since then with no reports issued.

3. Low degree of modification

The scientific research team behind KYSENSE® have previously developed many market leading products and as such have a wealth of experience in the development and advancement of HA dermal fillers. KYSENSE® benefits hugely from this experience and the advanced technology (HA Protect) preserves the long HA chains during the cross-linking process by removing the destructive oxygen.

This process means there is less cross-linking agent (BDDE) used, to an almost undetectable level, leading to a very low degree of modification (the amount of cross-linking chemical in relation to the amount of HA chains). Ultimately this leads to the supple and high projecting properties of KYSENSE® and respects all four of the rheological parameters that make up a great filler product.

4. High volumising power

KYSENSE® has unique rheological properties which offer high volumising power with minimum risk of migration.

The key rheological parameters which optimise aesthetic outcomes, safety and patient satisfaction are: Viscosity; Normal force of Compression (Static); Shear stress; Compression test in dynamic mode.

Published studies have shown that KYSENSE® Extreme exhibiting 34% more projection height than the global market leading volumising product and 17% more than another leading volumising filler. The study also concluded that 24% LESS volume of KYSENSE® Extreme was required to achieve the same result. It is this unique volumising power which gives KYSENSE® the unique ‘less is more’ quality.

Over the KYSENSE® range 20-30% less product is needed. The key is to treat to result (not to volume). It really is about the skill not the mL. (Gavard Molliard et al 2018; Bon Betemps et al 2018; CE study).

5. Ease of use

KYSENSE® is delivered via a lightweight, polymer syringe with integrated luer lock, combined with a comfortable finger grip and plunger rod. The TSK HPC needles provided in the KYSENSE® box have a 60% bigger inner diameter, this allows the best possible flow rate for a smoother extrusion force and more controlled injection. Needles are thin and ultra-sharp, TSK show the lowest traumatic effect for the patient. The hard polymer HPC advanced hub improves flow rates and allows for a tighter luer lock connection due to built-in exterior threading. No flexing, no needle pop off.

( Studies have demonstrated that the extrusion force for KYSENSE® products is comfortable and optimal to ensure injector comfort but also to limit speed of injection, in order to minimise extracellular dilaceration, bruising etc and to maximise injection precision. The injectors who took part in the clinical study, using the entire KYSENSE® range were ‘very satisfied’ or ‘satisfied’ for 100% of the injections they performed with KYSENSE®.

6. Patient & practitioner satisfaction

During the KYSENSE® clinical study 50 patients were injected with KYSENSE® products, with a total of 110 injected areas being treated. The study’s independent assessor observed an aesthetic improvement in 95% of injected sites one month after treatment. Six and twelve months after injection 93% and 81% respectively still showed an improvement.

The patients reported improvement in 97% of injection sites one month after treatment and 94% and 90% respectively after six months and twelve months. This high patient satisfaction leads to repeat bookings and recommendations. Furthermore, KYSENSE® performed very highly on longevity with all the products in the range lasting to 12 months.

7. Versatile range

There are 4 formulations in the KYSENSE® range to treat a wide range of indications.

  1. KYSENSE® Extreme – for facial sculpting, contouring and shaping (cheeks, jawline and chin)
  2. KYSENSE® Volume – for facial volumising (temples, cheeks and sub malar area)
  3. KYSENSE® Define – for facial dynamic expression (lips, marionette lines and nasolabial folds)
  4. KYSENSE® Precise – for skin finishing (perioral lines and superficial wrinkles)

8. Natural looking results

One of the key objectives in the development of KYSENSE® ® was to provide natural results with high patient satisfaction over repeat treatments, and to maintain the natural beauty of the patient. With your patients increasingly seeking natural looking results KYSENSE® is the perfect choice of product for your clinic. With unique ‘less is more’ rheological properties natural, long lasting results can be easily achieved.

9. Brand support

Circa Skin Ltd have a vision to provide a premium, safe HA dermal filler as good as or better than the market leading products and have teamed up with industry leading marketing experts to provide all the resources you require to support and grow your business. Specialist training is provided by a highly experienced team of clinicians and KYSENSE® customers also have exclusive access to the ‘Elevate to Expert’ online platform which provides a wealth of clinical, business and marketing resources.

10. Commercial partnership

KYSENSE® is available in boxes of 4 x 1ml syringes and is priced at £75 per 1ml across the range, which is comparable with other market leading brands. However, Circa Skin Ltd offer a unique subscription service to save you money AND time. By setting up an ‘autoship’ subscription your KYSENSE® will be delivered automatically to you every month, saving you precious time in ordering stock, leaving you free to other activities and increasing your clinic profit margins.

The subscription levels are outlined below:

Author: Nikki Zanna RN NIP
Halo Aesthetics

Nikki is a Registered Nurse Prescriber and is the founder of Halo Aesthetics as well as the Clinical Director. Nikki is highly skilled with over a decade of experience in Aesthetics. With her natural artistic flair Nikki has developed an Artistry in Aesthetics™ approach to ensure your results are beautifully balanced and natural looking every time. Nikki is a member of the British Association of Cosmetic Nurses.